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Cholesterol should be put in perspective

Dr. Donohue
Published on April 12th, 2008
Published on January 7th, 2010
Dr. Donohue

DEAR DR. DONOHUE: I am 87 years old and weigh 114 pounds. My cholesterol is 238 mg/dL (6.2 mmol/L). My LDL cholesterol is 140 (3.6) and my HDL cholesterol is 56 (1.5). My doctor has had me on five different cholesterol medicines, and every one of them caused muscle pain. Is there any medicine that doesn't cause muscle pain? I eat fish three times a week. I eat mostly fruits and vegetables, and lots of fiber. I eat whole wheat. I never eat red meat. What more can I do?
E.M.
ANSWER: You're doing everything you can. Your diet is perfect. The medicines that gave you muscle pain were probably the statin drugs - Zocor, Pravachol, Crestor, Lescol, Lipitor and Mevacor. They are the most-often- prescribed cholesterol-lowering medicines, and they are the ones most often implicated with muscle pain. There are other cholesterol-lowering medicines not related to statins - Niacin, Questran, Welchol, Colestid, Lopid and Tricor, and they don't usually cause muscle pain. However, do you really need a cholesterol drug?
Your total cholesterol is slightly over the desirable 200 (5.2) mark, but it's within a range called borderline high - not something to lose a lot of sleep over. Your good HDL cholesterol is just fine. Your bad LDL cholesterol is slightly high, but again it's in a range called borderline high. I don't believe you have a big worry. We have all gone crazy over cholesterol because it's given in a number by which we can judge "healthiness."
That's putting too much emphasis on one health factor. Others are equally important: blood pressure, diabetes, smoking, obesity, peripheral artery disease. You apparently have no other great risks for heart disease or stroke. You can be a little less cholesterol-vigilant, especially at your age.
I entered your information into the Framingham Risk Calculator. According to this evaluation, at your present cholesterol level you have a six per cent chance of having a heart attack in the next 10 years. If you lower your cholesterol to 200 (5.2), you have a 5 percent chance - not exactly an eye-popping change. Common sense ought to intervene here. Ask your doctor if you can ease up on cholesterol medication. I believe you can.
The booklet on cholesterol explains this national obsession in detail. Readers can order a copy by writing: Dr. Donohue - No. 201, Box 536475, Orlando, FL 32853-6475. Enclose a cheque or money order (no cash) for $6 with the recipient's printed name and address.
rrrr
DEAR DR. DONOHUE: In the paper, you listed 13 drugs for high cholesterol. Every one of those drugs has bad side effects. Maybe it's better to control cholesterol with diet and exercise. I wouldn't take those drugs even if someone gave me a million dollars. After all, no one lives forever in this dictatorship world.
Anon
ANSWER: No one argues with you. Cholesterol lowering should begin with a change in diet and with exercise.
How did you manage to work a "dictatorship world" into this discussion?

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